How The Top Women In Business Transformed Industries In 2025

Key Concepts

• Mindset as Foundation: Building a lasting legacy is fundamentally rooted in one’s mindset.
• Respin Health: A wellness company focused on women’s health, specifically addressing the menopause gap in healthcare.
• Forbes 50 Over 50: A list recognizing individuals over 50 making significant impacts.
• Washington Spirit & Michelle Kang: Revolutionizing women’s soccer through strategic ownership and business acumen.
• Iterative Entrepreneurship: The process of learning through action, embracing mistakes, and continuously improving.
• Ecosystem Reinvestment: The importance of giving back to the entrepreneurial community and supporting emerging talent.
• Comfort Zone Expansion: Achieving significant growth by actively seeking and embracing discomfort.

Dominating in 2025: Lessons from Forbes Women

This compilation of interviews with successful female entrepreneurs, featured by Forbes, highlights the common threads of vision, grit, and a strong core mindset that drive monumental business achievements. The central theme is that impactful change doesn’t wait for perfect conditions; it requires proactive initiation.

The Menopause Healthcare Gap: Halley Bry & Respin Health

Oscar-winning actor Halley Bry transitioned into entrepreneurship with the launch of Respin Health, a company dedicated to addressing the significant gaps in women’s healthcare, specifically surrounding menopause. This venture was spurred by Bry’s own misdiagnosis – initially told she had herpes when experiencing perimenopause symptoms. This experience revealed a critical lack of medical education, with only 13% of doctors in the US adequately trained to understand the menopausal body.

Bry emphasizes the urgent need for increased education for healthcare professionals, advocating for federal and state funding to support this retooling. She powerfully states, “when you know better, you do better,” and asserts that women deserve healthcare providers equipped to address their specific needs. Respin Health aims to be a comprehensive resource, offering information, coaching, nutritional guidance, and personalized exercise plans.

Revolutionizing Women’s Soccer: Michelle Kang & the Washington Spirit

Michelle Kang, majority owner of the Washington Spirit and ranked fifth on Forbes’ list of the most powerful women in US sports, is focused on transforming the landscape of women’s soccer. Her upbringing, influenced by her father’s belief in equal opportunity, instilled a strong work ethic and ambition. Kang funded her first year of college with money originally saved for her wedding, demonstrating early commitment to her goals.

Kang’s career followed a deliberate 30-year plan: consulting to gain broad business knowledge, leadership development within large organizations, and ultimately, leading a major company. She applied unconventional, disruptive thinking – akin to Uber’s impact on transportation – to improve efficiency and quality in healthcare tech with Cognizant. She recalls a pivotal moment in 2004 when President Bush invested in electronic medical records, but established companies lacked the innovative approach needed to capitalize on the opportunity. Kang believes in reinvesting in the ecosystem, supporting promising ventures and individuals who helped her along the way.

The Power of Transition & Early Entrepreneurial Spirit

Forbes events, including the 30 Under 30 Summit and the BLK Summit, showcased the economic power of cities like Atlanta and Columbus, Ohio. Candy Burus, a successful figure in entertainment, and Lucy Guo, co-founder of AI startup Scale and founder of Passes, exemplify the power of career transitions.

Guo cites Queen Latifah, Steve Harvey, and LL Cool J as inspirations, noting their ability to successfully pivot between diverse fields. She recounts a friend recognizing Guo’s own successful transition, leading to a moment of self-reflection and affirmation. Guo’s early entrepreneurial ventures, such as registering domain names and monetizing traffic for TV show trailers in fifth grade, demonstrate a precocious understanding of online business. Her key takeaway is to “optimize for learning” and to “always be willing to help people out,” believing in the power of karma and reinvesting in the entrepreneurial ecosystem.

Embracing Discomfort & Taking Action: Emma Greedy & Good American

Emma Greedy, CEO of Good American, emphasizes the importance of pushing past one’s comfort zone to achieve professional growth. She left a corporate job believing she could build something better, acknowledging that her first venture was imperfect but a valuable learning experience.

Greedy stresses that the “right time” for taking action never truly arrives, and that perfection is not a prerequisite for starting. She advocates for simply “going for it,” learning through iteration, and recognizing that self-perception is often more critical than external judgment. Her core message is encapsulated in the statement: “Nobody is watching you like you're watching you.”

Conclusion

The Forbes women featured in these interviews demonstrate a consistent pattern of proactive action, a willingness to learn from mistakes, and a commitment to supporting others. The overarching message is clear: impactful change doesn’t require waiting for ideal circumstances. It demands a strong mindset, a willingness to embrace discomfort, and the courage to simply start. The perfect time to make an impact never arrives – so the key is to begin, iterate, and grow.