Exposing the Monsanto Conspiracy

By Veritasium

ScienceBusinessTechnology
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Key Concepts

  • Selective Herbicides: Chemicals that kill specific types of plants (weeds) while leaving desired crops unharmed.
  • 2,4-D and 2,4,5-T: Early selective herbicides developed in the 1940s.
  • Dioxin: A highly toxic byproduct formed during the manufacturing of 2,4,5-T.
  • Agent Orange: A defoliant used during the Vietnam War, composed of a 50/50 mix of 2,4-D and 2,4,5-T, heavily contaminated with dioxin.
  • Glyphosate: The active ingredient in Roundup, a broad-spectrum herbicide.
  • Shikimate Pathway: A metabolic pathway essential for plant survival, targeted by glyphosate.
  • EPSPS Enzyme: An enzyme crucial in the Shikimate pathway, blocked by glyphosate.
  • Roundup Ready: Genetically modified (GMO) crops resistant to glyphosate.
  • Technology Use Agreement: Contracts farmers signed with Monsanto, restricting seed saving and granting Monsanto access to their land.
  • IARC (International Agency for Research on Cancer): An independent science panel that classified glyphosate as "probably carcinogenic to humans" in 2015.
  • Non-Hodgkin's Lymphoma (NHL): A type of cancer linked to glyphosate exposure.
  • Monsanto Papers: Internal Monsanto documents released during lawsuits, revealing manipulation of scientific research and regulatory processes.
  • "Let Nothing Go" Strategy: Monsanto's aggressive PR strategy to discredit any negative information about their products.
  • Genotoxicity: The ability of a substance to damage DNA.

The Rise of Selective Herbicides

  • In 1942, Franklin D. Jones discovered that the hormone 2,4-D could kill poison ivy by causing uncontrollable growth.
  • 2,4-D is an acid with a benzene ring and two chlorine atoms at the 2 and 4 positions.
  • Jones found that 2,4-D was selective, killing broad-leaved weeds while leaving grasses like wheat, corn, and barley mostly unaffected.
  • He further improved this selectivity by adding another chlorine atom to create 2,4,5-T, which left grasses even more unscathed.
  • These discoveries led to the development of the first practically viable selective herbicides, replacing dangerous chemicals like arsenic and manual weeding.
  • Jones patented these herbicides in 1945, and after the war, they were commercialized under names like Weedone and Weed-A-Bomb.

Monsanto and the Dioxin Contamination

  • Monsanto became a major producer of 2,4,5-T at its Nitro, West Virginia factory.
  • In 1949, an explosion at the Nitro plant exposed workers to a black, stinking powder, causing severe skin lesions and other health problems.
  • Monsanto was unable to identify the cause of the workers' illness, despite marketing 2,4,5-T and 2,4-D as very safe.
  • In 1957, German dermatologist Karl Schulz discovered that the lesions were caused by dioxin, a byproduct formed during 2,4,5-T production at temperatures slightly above 170 degrees Celsius.
  • Dioxin forms when two molecules of trichlorophenol (TCP) fuse together.
  • Schulz warned major chemical companies, including Monsanto and Dow, about the dioxin contamination, but Monsanto denied receiving the letters, and Dow claimed to have misfiled them.
  • Despite knowing the danger, Monsanto did not warn the public, as their herbicide business was booming.

Agent Orange and the Vietnam War

  • During the Vietnam War, the US used Agent Orange, a 50/50 mix of 2,4-D and 2,4,5-T, to defoliate jungles and destroy Viet Cong cover.
  • Monsanto was the largest supplier of Agent Orange.
  • Agent Orange was heavily contaminated with dioxin, causing severe health problems for civilians and soldiers on both sides, including skin diseases, cancer, and birth defects.
  • Dow acknowledged in internal letters that dioxin was "the most toxic compound they have ever experienced" and caused incapacitating acne.
  • The US sprayed South Vietnam with 72 million liters of Agent Orange, containing approximately 80 liters of dioxin.
  • By some estimates, as many as three million people suffered from the effects of Agent Orange.
  • In 1967, 5,000 scientists signed a petition condemning the use of herbicides in Vietnam.

The Discovery of Glyphosate and Roundup

  • Facing scrutiny over dioxin contamination, Monsanto sought a safer herbicide to replace 2,4,5-T.
  • After nine years of research, John E. Franz discovered glyphosate in 1970.
  • Glyphosate works by blocking the EPSPS enzyme in the Shikimate pathway, which is essential for plant survival.
  • The Shikimate pathway is unique to plants, bacteria, and fungi, not found in humans or animals.
  • Monsanto marketed glyphosate as safe because it targeted an enzyme not found in humans or pets and because it was biodegradable.
  • In 1974, Monsanto launched Roundup, a glyphosate-based herbicide.
  • Roundup killed all weeds, not just broad-leaved ones, allowing farmers to practice no-till farming.
  • Monsanto marketed Roundup as safer than table salt and safe enough to drink.

Roundup Ready Crops and Monsanto's Monopoly

  • By the late 1980s, Monsanto was selling seven million pounds of Roundup annually, generating a billion dollars in revenue.
  • Glyphosate's unique molecular structure prevented competitors from creating similar herbicides without violating Monsanto's patents.
  • To further dominate the market, Monsanto developed Roundup Ready crops, genetically modified to be resistant to glyphosate.
  • In 1985, Calgene published a paper showing that they had made tobacco slightly resistant to glyphosate, spurring Monsanto to accelerate their research.
  • Monsanto scientists found a strain of salmonella in sludge near their glyphosate factories that had evolved a way to mutate its EPSPS enzyme, making it resistant to glyphosate.
  • They used a gene gun to insert the salmonella DNA into plant cells, creating Roundup Ready crops.
  • By 1998, Monsanto had patents for glyphosate-resistant canola, corn, and cotton.
  • By 2001, over 70% of all soybeans grown in the US were Monsanto's Roundup Ready varieties.

The Technology Use Agreement and Farmer Control

  • Farmers who used Roundup Ready seeds had to sign Monsanto's Technology Use Agreement, which prohibited seed saving, sharing, or selling.
  • The agreement also granted Monsanto access to farmers' land to examine crops and take samples.
  • Monsanto aggressively enforced these agreements, sending private detectives, ex-cops, and aerial surveillance to monitor farms for patent infringement.
  • They even had a hotline (1-800-ROUNDUP) for farmers to report on their neighbors.
  • By 2013, Monsanto had sued over 400 farmers, raking in over $20 million.
  • Many farmers went bankrupt or settled out of court due to the high legal costs.
  • The culture of fear and paranoia turned neighbors against each other, especially in communities where some farmers did not use Monsanto's system.

The Murder of Mike Wallace and Dicamba Drift

  • Mike Wallace, an Arkansas farmer who did not use Monsanto's herbicide system, was murdered in 2016.
  • Wallace suspected that Dicamba, another Monsanto herbicide, had drifted from a neighboring farm, killing his soybean crop.
  • Tensions between Wallace and the neighboring farm escalated, leading to a confrontation and Wallace's death.

The IARC Classification and the Monsanto Papers

  • On March 20, 2015, the International Agency for Research on Cancer (IARC) classified glyphosate as "probably carcinogenic to humans."
  • This contradicted the findings of other organizations, such as the EPA and the World Health Organization.
  • California lawyer Brent Wisner investigated Monsanto and discovered internal documents (the Monsanto Papers) revealing manipulation of scientific research and regulatory processes.
  • The Monsanto Papers showed that Monsanto had suppressed data showing that glyphosate caused kidney tumors in mice, ghostwritten safety studies, and colluded with corrupt EPA officials.
  • Wisner released the Monsanto Papers to the public, sparking outrage and a wave of lawsuits against Monsanto.

Lawsuits and Bayer's Acquisition of Monsanto

  • By mid-2017, Wisner released the Monsanto Papers to the public, now known as the Monsanto Papers.
  • By the end of 2017, over 3,000 victims had signed onto the case.
  • To discredit the IARC classification, Monsanto ghostwrote review papers criticizing their decision.
  • Monsanto employed a "Let Nothing Go" strategy to aggressively defend its products and discredit critics.
  • In 2018, Bayer acquired Monsanto, inheriting the Roundup lawsuits.
  • The first case against Monsanto-Bayer went to trial, and the jury sided with the plaintiff, Dewayne Lee Johnson, awarding him $289 million in damages.
  • By 2025, Bayer had settled over a hundred thousand cancer lawsuits for over $10 billion.

The Dangers of Glyphosate and the Future of Herbicides

  • IARC's classification of glyphosate as a probable carcinogen is based on evidence of genotoxicity and disruption of the gut microbiome.
  • High exposure to glyphosate is associated with a modest increase in the risk of certain cancers.
  • The EPA and other organizations still disagree with the IARC classification, but courts have repeatedly criticized the EPA's assessment of glyphosate.
  • Many studies on glyphosate safety are industry-funded, raising concerns about bias.
  • Bayer has removed glyphosate from some commercial products due to public backlash and the development of glyphosate-resistant weeds.
  • Many Roundup sprays now contain 2,4-D, bringing the industry full circle.
  • The video emphasizes the importance of protecting sensitive individuals and creating firewalls between regulators and the regulated to ensure scientific integrity.

Conclusion

The video details the history of Monsanto, from its early development of selective herbicides like 2,4-D and 2,4,5-T to its dominance of the agricultural market with Roundup and Roundup Ready crops. It exposes the company's manipulation of scientific research, collusion with regulatory agencies, and aggressive tactics to control farmers. The video highlights the dangers of glyphosate and the importance of independent scientific research and regulatory oversight to protect public health and the environment. The story serves as a cautionary tale about the potential consequences of unchecked corporate power and the need for transparency and accountability in the agricultural industry.

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